About EnliTISA

EnliTISA’s vision is to improve the lives of patients with inflammatory and fibrotic diseases through the discovery and development of breakthrough therapies.


EnliTISA is a clinical stage biopharmaceutical company focused on developing novel therapeutics with a primary focus on inflammatory and fibrotic conditions with unmet medical needs.

EnliTISA, based in Shanghai, China, was founded by Chinese and Swedish team members in 2021, and is focusing on anti-inflammatory and anti-fibrosis multi-innovative drug development. The Chinese-Swedish team collaborates on pre-clinical and clinical development of drugs in China, Europe and the US.

All projects in the pipeline are based on the inventions made by the EnliTlSA team. As of now, 16 international PcT invention patents have
been applied for, 3 Chinese invention patents have been granted, and 18 international invention patents have been granted.

2021

Founded in

16

International invention patents

Latest Progress on Two Innovative Drugs:‌
TISA-818‌, a novel chemical entity (NCE), is being developed for the treatment of acute respiratory distress syndrome (ARDS), idiopathic pulmonary fibrosis (IPF), radiation-induced oral mucositis (SOM), and chronic obstructive pulmonary disease (COPD).
  • ARDS‌: Phase II clinical trials are underway in China, with completion of patient enrollment anticipated by March 2025.
  • COPD‌: Preparations are ongoing to submit applications for clinical trial authorization.
  • IPF‌: Phase I clinical trials have been completed in Europe.
  • SOM‌: A Phase Ib clinical trial has been initiated in China, expected to conclude in the second quarter of 2025.
  • Montelukast Sodium Gel‌, a highly potent, low-toxicity, and safe leukotriene receptor antagonist, has expanded its therapeutic scope through formulation innovation. It is now indicated for postoperative hemorrhoid care, burn wounds, chronic wounds, and radiation proctitis. The development and production rights for these four indications in mainland China have been licensed to ‌Shanghai Pharmaceutical (Group) Co., Ltd.‌. To date, Phase IIa clinical trials have been completed for ‌postoperative hemorrhoid management‌ and ‌radiation proctitis‌.

Organizational


organizational

Our team


team

Co-founders


Bengt Ingemar Samuelsson

Bengt Ingemar Samuelsson

Nobel Prize winner, second largest shareholder, director of Shanghai company, chairman of Sweden subsidiary


· Rich accumulation of basic research on inflammation: 1982 Nobel Prize in Physiology or Medicine: Prostaglandins and related active substances · Rich experience in transformation of achievements: Originally developed montelukast sodium, celecoxib, Xlata, etc., and cooperated with Pfizer and Merck; served as director of 12 internationally renowned pharmaceutical companies and investment companies · Broad vision for basic research and industrial innovation: 12 years as dean of Karnarinska Institute in Sweden; 12 years as chairman of Nobel Foundation; nomination rights for Nobel Prize; Galen Award Jury

Jan-Christer  Janson

Jan-Christer Janson

Founding shareholder, director of Shanghai company, director of Sweden subsidiary


· Former Chief Scientist of Swedish Pharmacia Company · Protein and peptide purification and modification scientists · Winner of the International Science and Technology Cooperation Award of the People's Republic of China · Winner of Chinese Government Friendship Award

Gu Ming (Rainbow)

Gu Ming (Rainbow)

Founder, chairman and general manager


· Graduated from the State Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences with a master's degree and a doctorate degree; won the National Science and Technology Major Scientific and Technological Achievement Award · Postdoctoral fellow and visiting scholar at Uppsala University, Sweden, under the tutelage of Prof. Jan-Christer Janson; visiting researcher at Uppsala University

Leadership Team


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Gu Ming (Rainbow)

Founder, chairman and general manager


· Graduated from the State Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences with a master's degree and a doctorate degree; won the National Science and Technology Major Scientific and Technological Achievement Award · Postdoctoral fellow and visiting scholar at Uppsala University, Sweden, under the tutelage of Prof. Jan-Christer Janson; visiting researcher at Uppsala University

Ru Hui


Ru Hui

Lars Öhman


Lars Öhman

Board members of EnliTISA Shanghai or Swedish daughter company


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Bengt Ingemar Samuelsson

Nobel Prize winner, second largest shareholder, director of Shanghai company, chairman of Sweden subsidiary


· Rich accumulation of basic research on inflammation: 1982 Nobel Prize in Physiology or Medicine: Prostaglandins and related active substances · Rich experience in transformation of achievements: Originally developed montelukast sodium, celecoxib, Xlata, etc., and cooperated with Pfizer and Merck; served as director of 12 internationally renowned pharmaceutical companies and investment companies · Broad vision for basic research and industrial innovation: 12 years as dean of Karnarinska Institute in Sweden; 12 years as chairman of Nobel Foundation; nomination rights for Nobel Prize; Galen Award Jury

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Jan-Christer Janson

Founding shareholder, director of Shanghai company, director of Sweden subsidiary


· Former Chief Scientist of Swedish Pharmacia Company · Protein and peptide purification and modification scientists · Winner of the International Science and Technology Cooperation Award of the People's Republic of China · Winner of Chinese Government Friendship Award

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Jesper Zacharias Haeggstrom

Core member, director of Swedish subsidiary; Professor Samuelsson


· Focus on basic research on inflammation, including new target research; deeply cultivate the basis of arachidonic acid inflammation, and discover drug candidates from substances produced by the human body to fight inflammation and damage · Vice-Chairman of the Nobel Prize Review Committee for Medical Physiology

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Gu Ming (Rainbow)

Founder, chairman and general manager


· Graduated from the State Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences with a master's degree and a doctorate degree; won the National Science and Technology Major Scientific and Technological Achievement Award · Postdoctoral fellow and visiting scholar at Uppsala University, Sweden, under the tutelage of Prof. Jan-Christer Janson; visiting researcher at Uppsala University

Scientific affair & regulatory affair team


Anders Kärnell


Anders Kärnell

Jiang Taotao (Cathy)


Jiang Taotao (Cathy)

Kang Ruijuan (Alicia)


Kang Ruijuan (Alicia)


Culture

Enlitisa

Corporate Mission

Corporate Mission

To be an original research and innovation drug enterprise with strong vitality and fighting power

Corporate Vision

Corporate Vision

To be an original research and innovation drug enterprise with strong vitality and fighting power, and repay the support of shareholders, society and the government with good drugs and taxes that can withstand the years

Property


Authorized Patent of Invention (US)


Authorized Patent of Invention (US)

Authorized Patent of Invention (CN)


Authorized Patent of Invention (CN)

Authorized Patent of Invention (CN)


Authorized Patent of Invention (CN)

Authorized Patent of Invention (CN)


Authorized Patent of Invention (CN)

Honor


2024 Shanghai Top 50 Most Investment-Promising Startups


2024 Shanghai Top 50 Most Investment-Promising Startups

Top 50 Innovation & Entrepreneurship Enterprises list of the China Innovation & Entrepreneurship Competition


Top 50 Innovation & Entrepreneurship Enterprises list of the China Innovation & Entrepreneurship Competition

Second Prize in the Bio-medicine National Competition of the 13th China Innovation & Entrepreneurship Grand Prix


Second Prize in the Bio-medicine National Competition of the 13th China Innovation & Entrepreneurship Grand Prix

National High-tech Enterprise


National High-tech Enterprise