R & D background
R & D pipeline

Two projects are in clinical trial stage:
UP818
UP818, a new chemical entity with new mechanism, is intended to be used for Acute Lung Injury (ALI) and Acute Respiratory Distress Syndrome (ARDS) by i.v. and for Idiopathic Pulmonary Fibrosis (IPF) by s.c. Phase I study of i.v. on healthy volunteers in Hua Shan Hospital, Shanghai, China, is completing by the end of 2022. Phase II study on ARDS is planning to start in May, 2023. It is planning to submit CTA to Swedish MPA in June, 2023 and start clinical trial phase I in September, 2023, in Sweden.
Montelukast sodium
Montelukast sodium topical sterile gel for anorectal surgery and radiation proctitis. China mainland has been licensed to Shanghai Pharma, who is the sponsor for clinical trial and further development. Phase I study on healthy volunteers has been completed. Phase II studies on the two indications are planning to start in January and February, 2023.
Intellectual Property
12 patent applications by PCT
Number
First Submission Date
Application No
1
2017/07/05
PCT/CN2018/094441
2
2019/01/10
PCT/CN2020/071337
3
2021/08/06
PCT/CN2018/111247
4
2018/09/14
PCT/CN2019/105832
5
2017/07/05
PCT/CN2018/094441
6
2017/05/28
PCT/CN2019/088593
7
2017/07/05
PCT/CN2020/114828
8
2017/12/02
PCT/CN2020/133436
9
2017/03/17
PCT/CN2021/081361
10
2017/03/17
PCT/CN2021/081362
11
2017/12/02
PCT/CN2020/133438
12
2017/12/12
PCT/CN2020/133439
Two in China and one in US have been authorized
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